Myb30-interacting e3 ligase 1
WebIn addition, an apple RING E3 ubiquitin ligase MYB30-INTERACTING E3 LIGASE 1 (MdMIEL1) was identified to be an MdMYB308L-interacting protein and promoted the … WebMar 31, 2024 · MYB30-INTERACTING E3 LIGASE 1 (MIEL1) E3 ubiquitin ligase controls the protein stability of the two MYB transcription factors, MYB96 and MYB30, and thereby …
Myb30-interacting e3 ligase 1
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WebAug 11, 2024 · PI4Kγ2 was shown to interact with MIEL1, regulating its degradation and further the stability of transcription factor MYB30, which suppresses auxin metabolism by directly binding to promoter... MIEL1 is an E3 Ub ligase that commonly facilitates protein degradation through physical interactions with a target substrate34. Therefore, we asked which protein might be a regulatory target of MIEL1 in the regulation of ABA sensitivity. We performed a yeast-two-hybrid (Y2H) screen and identified a … See more Ubiquitination is a representative molecular mechanism that regulates ABA signalling20,22,24. To further understand the ABA signalling network, … See more The physical interactions of MIEL1 with MYB96 led us to examine whether MIEL1 ubiquitinates MYB96. To examine ubiquitination of MYB96 by MIEL1 in … See more The ABA sensitivity phenotype and altered accumulation of MYB96 in miel1 mutants suggest that a MIEL1-MYB96 signalling module may be required for proper ABA … See more To confirm the genetic hierarchy between MIEL1 and MYB96, we crossed the miel1-1 mutant with myb96-1 and measured the germination percentage. In the … See more
WebSep 12, 2016 · Here we show that the RING-type E3 ligase MYB30-INTERACTING E3 LIGASE 1 (MIEL1) regulates ABA sensitivity by promoting MYB96 turnover in Arabidopsis. Germination of MIEL1-deficient mutant seeds is hypersensitive to ABA, whereas MIEL1-overexpressing transgenic seeds are less sensitive. MIEL1 can interact with MYB96, a … WebAug 11, 2024 · Recent genetic studies have revealed important roles of distinct E3 ligases in phytohormone signaling pathways ( Kelley, 2024 ), operating via the degradation of various components, including receptors, positive or negative regulators, or those related to hormone metabolisms.
WebApr 6, 2024 · Phylogenetic analysis showed that the protein encoded by GRMZM2G056270 was closely related to the MYB30-INTERACTING E3 LIGASE 1 (MIEL1) proteins from Sorghum bicolor and Setaria italica (91.27% and 88.5% similar at the amino acid level, respectively; Figure S1), and that they cluster with AtMIEL1 (Figure 1c) from Arabidopsis, … WebUbiquitination is a major type of post-translational modification of proteins in eukaryotes. The plant U-Box (PUB) E3 ligase is the smallest family in the E3 ligase superfamily, but plays a variety of essential roles in plant growth, development and response to diverse environmental stresses. Hence, PUBs are potential gene resources for developing climate …
WebApr 8, 2024 · In the present study, we discovered that endothelial FAT1 promotes basal YAP/TAZ protein turnover by interacting with the E3 ligase MIB2, leading to their subsequent ubiquitin-dependent degradation.
ky board pharmacyWebMar 23, 2024 · The plant U-box (PUB) proteins are a type of E3 ubiquitin ligases well known for their functions in response to various stresses. They are also related to fruit development and ripening. ... Protein-protein interaction analysis suggested that FaU-box members could interact with each other as well as other proteins involved in hormone signaling ... ky board of nursing applicationWebSep 15, 2024 · Finally, the molecular mechanism by which this MdMYB1-interacting RING E3 ligase regulates anthocyanin accumulation is analyzed and discussed. Results MdMIEL1 negatively regulates anthocyanin accumulation Yeast two-hybrid (Y2H) screening through an apple cDNA library was performed using MdMYB1 as a bait. ky business property taxWebRING-finger-containing E3 ubiquitin ligases play important roles in plant response to biotic and abiotoc stresses. In this study, through homology analysis, a Malus × domestica … proform 625 treadmill weight limitWebAtrophin 1 Interacting Protein 4 (AIP4) (also named Itch) is a HECT-type E3 ubiquitin–protein ligase and is a member of the neural precursor cell-expressed developmentally downregulated gene 4 (Nedd4) family . Various proteins, including Nedd4, Smurf1, WWP2, AIP4/Itch, and Rsp5p are members of the Nedd4 family. proform 635cwWebThe deduced 301-amino acid protein has a calculated molecular mass of 34 kD. NOSIP shares 46% and 29% amino acid identity with orthologs in C. elegans and A. thaliana, respectively. Northern blot analysis detected a 1.2-kb NOSIP transcript that was highly expressed in human heart and brain, with lower levels in lung and skeletal muscle. proform 625ex treadmill motor control boardWebApr 1, 2024 · MYB30-INTERACTING E3 LIGASE 1 (MIEL1), one RING-type E3 ligase, also repress anthocyanin synthesis by degrading MdMYB308L. In Arabidopsis, a MAP Kinase, AtMPK4 phosphorylate and enhance the activity of MYB75 to promote anthocyanin synthesis. [B] Post-translational regulation of flavonol synthesis in Okra. proform 626 exp treadmill