WebFeb 16, 2024 · Generic name: cisplatin [ sis-PLA-tin ] Drug class: Alkylating agents. Medically reviewed by Drugs.com on Feb 16, 2024. Written by Cerner Multum. The Platinol brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available. Uses; WebCisplatin is the generic name for the trade name drug Platinol® and Platinol®-AQ. In some cases, health care professionals may use the trade name Platinol® and Platinol® …
Cisplatin - LiverTox - NCBI Bookshelf
WebThere are five traditional categories of alkylating agents: Nitrogen mustards (eg, bendamustine, chlorambucil, cyclophosphamide, ifosfamide, mechlorethamine, melphalan) Nitrosoureas (eg, carmustine, lomustine, streptozocin) Alkyl sulfonates (eg, busulfan) Triazines (eg, dacarbazine, temozolomide) Ethylenimines (eg, altretamine, thiotepa) WebSep 15, 2024 · SIDE EFFECTS. Nephrotoxicity - Dose-related and cumulative renal insufficiency is the major dose-limiting toxicity of cis-platin.Renal toxicity has been noted in 28% to 36% of patients treated with a single dose of 50 mg/m 2.It is first noted during the second week after a dose and is manifested by elevations in BUN and creatinine, serum … cities near va beach
Cisplatin dosing, indications, interactions, adverse effects …
WebGC is the name of a chemotherapy combination that includes: gemcitabine cisplatin It is a treatment for a number of different types of cancer. How GC works These chemotherapy … Cisplatin is a chemotherapy medication used to treat a number of cancers. These include testicular cancer, ovarian cancer, cervical cancer, bladder cancer, head and neck cancer, esophageal cancer, lung cancer, mesothelioma, brain tumors and neuroblastoma. It is given by injection into a vein. Common side … See more Cisplatin is administered intravenously as short-term infusion in normal saline for treatment of solid and haematological malignancies. It is used to treat various types of cancers, including sarcomas, some See more Cisplatin is the square planar coordination complex cis-[Pt(NH3)2Cl2]. The prefix cis indicates the cis isomer in which two similar ligands are in … See more Syntheses of cisplatin start from potassium tetrachloroplatinate. Several procedures are available. One obstacle is the facile formation of Magnus's green salt (MGS), which has the same empirical formula as cisplatin. The traditional way to avoid MGS involves the … See more Cisplatin has a number of side effects that can limit its use: • Nephrotoxicity (kidney damage) is the primary dose … See more Cisplatin interferes with DNA replication, which kills the fastest proliferating cells, which in theory are cancerous. Following administration, one … See more The compound cis-[Pt(NH3)2Cl2] was first described by Italian chemist Michele Peyrone in 1845, and known for a long time as Peyrone's … See more Cisplatin has been studied with Auger therapy to increase the therapeutic effects of cisplatin, without increasing normal tissue toxicities. See more cities near venice italy